Catalytic Performance of a Supramolecular Bienzyme Complex Formed with Artificial Aminotransferase and Natural Lactate Dehydrogenase
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A supramolecular bienzyme complex was constituted in a combination of a catalytic bilayer membrane as an artificial aminotransferase with a natural lactate dehydrogenase and the resulting cooperative system enhanced the catalytic activity of the artificial enzyme to promote a sequential transformation of α-amino acids to the corresponding α-hydroxy acids via formation of α-keto acids, exhibiting a marked substrate specificity.
- Chemistry Letters
Chemistry Letters 1996(6), 427-428, 1996-06
The Chemical Society of Japan