Catalytic Performance of a Supramolecular Bienzyme Complex Formed with Artificial Aminotransferase and Natural Lactate Dehydrogenase
A supramolecular bienzyme complex was constituted in a combination of a catalytic bilayer membrane as an artificial aminotransferase with a natural lactate dehydrogenase and the resulting cooperative system enhanced the catalytic activity of the artificial enzyme to promote a sequential transformation of α-amino acids to the corresponding α-hydroxy acids via formation of α-keto acids, exhibiting a marked substrate specificity.
- Chemistry letters
Chemistry letters 1996(6), 427-428, 1996-06
The Chemical Society of Japan