Chiral Discrimination of 1-Phenylethylamine by Diastereomeric Salt Formation with Bile Acids. Crystal Structures of Cholic Acid Salts with(R)-and(S)-1-Phenylethylamine
Chiral discrimination of 1-phenylethylamine (<B>1</B>) by diastereomeric salt formation with bile acids is described. X-ray crystallographic studies of the salts between cholic acid (<B>2a</B>) and (<I>R</I>)-, (<I>S</I>)-, and (<I>RS</I>)-<B>1</B> reveal that more densely packed (<I>S</I>)-<B>1</B>+<B>2a</B> salt crystallizes preferentially by treatment of <B>2a</B> from racemic <B>1</B>.
- Chemistry letters
Chemistry letters 1996(10), 837-838, 1996-10
The Chemical Society of Japan