Bulky Thiols and Their Coordination Compounds. An Improvement of the Removal Method of Tetrahydropyranyl Group From Thiols and Its Application for Ligand Syntheses
The route for the syntheses of alkanthiols having bulky groups at the neighborhood of sulfur atoms was improved, and applied for the preparation of thiol ligands that mimic the cysteine containing metal binding sites in proteins. The new method developed the deprotection of tetrahydropyranyl group from α,α-diphenylalkyl 2-tetrahydropyranyl sulfides.
- Chemistry letters
Chemistry letters 1996(11), 999-1000, 1996-11
The Chemical Society of Japan