A New Method for ^<18>F-Labelling of Biochemical Molecules Using [^<18F>] Perfluoronitrobenzen and Its Application to ^<18>F-Labeling of Angiotensin II

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抄録

We propose a new method for labeling biochemical molecules with <I>fluorine</I>-18 (positron emitters) using [G-<SUP>18</SUP>F]polyfluoronitrobenzene as the reagent. Perfluoronitrobenzene was easily labeled with <SUP>18</SUP>F<SUP>−</SUP> by the <SUP>18</SUP>F- for-<SUP>19</SUP>F exchange reaction giving [G-<SUP>18</SUP>F]pentafluoronitrobenzene (PFNB, radiochemical yield 30-41 %) and the [G-<SUP>18</SUP>F]PFNB was applied successfully for <SUP>18</SUP>F-labeling of angiotensin II.

収録刊行物

  • Chemistry letters

    Chemistry letters 1997(2), 109-110, 1997-02

    The Chemical Society of Japan

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各種コード

  • NII論文ID(NAID)
    10002609474
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    03667022
  • データ提供元
    CJP書誌  J-STAGE 
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