Regioselective distal-Dibromination of Calixresorcinarene
The partial bromination of calixresorcinarene with a limited amount of <I>N</I>-bromosuccinimide was examined. The ratio of the two dibromo derivatives, <I>distal</I>- and <I>proximal</I>-isomers, was 10:1, which is much different from the statistical value of 1:2. The simple procedure for the preparation of the <I>distal</I>-dibromo derivative is described.
- Chemistry letters
Chemistry letters 1997(2), 185-186, 1997-02
The Chemical Society of Japan