Olefin-Insertion Reaction between the Carbonyls of Benzils ; Formation of 1, 4-Diketons by Michael Addition Catalyzed by Cyanide Ion
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Benzils (<B>1</B>) react with Michael addition acceptors (<B>2</B>) in the presence of cyanide ion as a catalyst to give 1,4-diketones (<B>3</B>), which are products of ethylene group insertion between the carbonyls of the benzils. The 1,4-diketones (<B>3</B>) are produced through the formation of the <I>O</I>-aroylmandelonitrile anion, followed by Michael addition and rearrangement of the aroyl group with decyanation.
- Chemistry Letters
Chemistry Letters 1997(8), 697-698, 1997-08
The Chemical Society of Japan