Esterase Catalyzed Regio-and Enantio-selective Hydrolysis of Substituted Carboxylates
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Optically active α-substituted carboxylic acid derivatives were obtained with regio- and enantio-selective hydrolysis catalyzed by esterase from <I>Pseudomonas putida</I> MR-2068. Substrate specificities were summarized in empirical rule to predict the enantiopreferences of the esterase. High regio-selectivities were also discussed with binding models.
- Chemistry Letters
Chemistry Letters 1997(8), 741-742, 1997-08
The Chemical Society of Japan