A Sequence of Palladium-Catalyzed Borylation of Allyl Acetates with Bis(pinacolato)diboron and Intramolecular Allylboration for the Cyclization of Oxo-2-alkenyl Acetates
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The cross-coupling reaction of bis(pinacolato)diboron with oxo-2-alkenyl acetates in toluene at 50 °C in the presence of Pd(dba)<SUB>2</SUB>/2 AsPh<SUB>3</SUB> (3 mol%) to give allylboronates was followed by the intramolecular allylboration at 100 °C. The sequence provided cyclic homoallyl alcohols in high yields.
- Chemistry Letters
Chemistry Letters 1997(8), 811-812, 1997-08
Chemical Society of Japan