Titanocene Induced Deoxygenation of Di-epoxides - A Convenient Regioselective Preparation of 1, 3-Diols
Titanocene induced regioselective opening of 2,4-di-epoxy alcohols to 1-ene-3,5-diols is described. Diepoxy alcohols were treated with 3 eq. of Cp<SUB>2</SUB>TiCl in dry THF to obtain 1-ene-3,5 diols with conservation of stereochemistry at C-3 and C-5 was observed.
- Chemistry letters
Chemistry letters 1997(9), 905-906, 1997-09
The Chemical Society of Japan