Titanocene Induced Deoxygenation of Di-epoxides - A Convenient Regioselective Preparation of 1,3-Diols

  • J S Yadav
    Indian Institute of Chemical TechnologyHyderabad - 500 007 , India
  • Dale Srinivas
    Indian Institute of Chemical TechnologyHyderabad - 500 007 , India

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Abstract

<jats:title>Abstract</jats:title> <jats:p>Titanocene induced regioselective opening of 2,4-di-epoxy alcohols to 1-ene-3,5-diols is described. Diepoxy alcohols were treated with 3 eq. of Cp2TiCl in dry THF to obtain 1-ene-3,5 diols with conservation of stereochemistry at C-3 and C-5 was observed.</jats:p>

Journal

  • Chemistry Letters

    Chemistry Letters 26 (9), 905-906, 1997-09-01

    Oxford University Press (OUP)

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