New Analogs of the Pyripyropene Family of ACAT Inhibitors via α-Pyrone Fragmentation and γ-Acylation/Cyclization

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著者

    • OBATA Rika
    • Research Center for Biological Function, The Kitasato Institute and School of Pharmaceutical Sciences, Kitasato University
    • SUNAZUKA Toshiaki
    • Research Center for Biological Function, The Kitasato Institute and School of Pharmaceutical Sciences, Kitasato University
    • TIAN Zhiming
    • Research Center for Biological Function, The Kitasato Institute and School of Pharmaceutical Sciences, Kitasato University
    • TOMODA Hiroshi
    • Research Center for Biological Function, The Kitasato Institute and School of Pharmaceutical Sciences, Kitasato University
    • HARIGAYA Yoshihiro
    • Research Center for Biological Function, The Kitasato Institute and School of Pharmaceutical Sciences, Kitasato University
    • OMURA Satoshi
    • Research Center for Biological Function, The Kitasato Institute and School of Pharmaceutical Sciences, Kitasato University
    • SMITH III Amos B.
    • Department of Chemistry, Monell Chemical Senses Center, and Laboratory for Research on the Structure of Matter, University of Pennsylvania

抄録

The pyridine moiety of pyripyropene A was replaced with other aromatic and heteroaromatic substituents via α-pyrone degradation followed by dienolate γ-acylation and in situ cyclization.

収録刊行物

  • Chemistry letters

    Chemistry letters 1997(9), 935-936, 1997-09

    The Chemical Society of Japan

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各種コード

  • NII論文ID(NAID)
    10002615104
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    03667022
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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