Lanthanide Triflate-Catalyzed Three-Component Coupling Reactions of Aldehydes, Hydroxylamines, and Alkenes Leading to Isoxazolidine Derivatives
Three-component coupling reactions of aldehydes, hydroxylamines, and alkenes proceeded smoothly in the presence of a catalytic amount of a lanthanide triflate, to afford isoxazolidine derivatives in high yields with high diastereoselectivities. The asymmetric 1,3-dipolar cycloaddition using a chiral lanthanide catalyst is also described.
- Chemistry letters
Chemistry letters 1997(10), 1039-1040, 1997-10
The Chemical Society of Japan