Genetic Polymorphism of ADA in Taiwan Aboriginal Populations: New ADA Variants Detected by Isoelectric Focusing Method.

  • JIN FENG
    Department of Anthropology, Graduate School of Science, University of Tokyo International Research Center for Japanese Studies
  • SAITOU NARUYA
    Department of Evolutionary Genetics, National Institute of Genetics
  • ISHIDA TAKAFUMI
    Department of Anthropology, Graduate School of Science, University of Tokyo
  • SUN CHEIH-SHAN
    Taidong Hospital
  • PAN I-HUNG
    Department of Bacteriology, College of Medicine, National Taiwan University
  • OMOTO KEIICHI
    Department of Anthropology, Graduate School of Science, University of Tokyo International Research Center for Japanese Studies
  • HORAI SATOSHI
    Department of Human Genetics, National Institute of Genetics

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  • Genetic Polymorphism of ADA in Taiwan A

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Abstract

ADA subtype polymorphism in nine aboriginal populations (Gaoshan) of Taiwan was studied by means of the IEF method. A new ADA variant allele, ADA*Taiwan1, was in a high allele frequency in two Gaoshan populations, the Amis and the Paiwans. Another new variant, ADA*Taiwan2, was found in only one case of heterozygote in the Saisiats. Allele frequencies of a common allele, ADA*2, in the Paiwans and the Amis were the highest among the Asian populations so far studied.

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