PIVKA-II IRMA「第一」^<【○!R】>の基礎および臨床的検討 Fundamental and Clinical Evaluation of a PIVKA-II Kit, "PIVKA-II IRMA 'Daiichi, ^<【○!R】>"

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<I>We evaluated the characteristics and clinical efficacy of the"PIVKA-II IRMA'Daiichi, <SUP>®</SUP>"kit for estimating the serum PIVKA-II levels in hepatocellular carcinoma patients. Intraassay and interassay variances were within 10%. Recovery and dilution tests also gave satisfactory results. There was no significant effect of reaction time on PIVKA-II levels. However, PIVKA-II levels were significantly lower in heparinized plasma than those in serum and EDTA plasma. The cut-off level was determined as 40</I>mAU/mL, <I>mean +3SD of PIVKA-11 level in 84 normal control subjects. The sensitivity and specificity of"PIVKA-IIIRMA lsquo;Daiichi, <SUP>®</SUP>"kit for hepatocellular carcinoma patients was 81; 6% and 82.4%, respectively. A significant correlation was observed between PIVKA-II levels measured by"PIVKA-II IRMA'Daiichi, <SUP>®</SUP>"kit and "EitestR Mono P II"EIA kit (r=979) . In conclusion, "PIV-KA-II IRMA'Daiichi, <SUP>®</SUP> kit is considered to be accurate and useful for measuring PIVKA-II levels in hepatocellular carcinoma patients.</I>

収録刊行物

  • Radioisotopes  

    Radioisotopes 48(3), 188-194, 1999-03-15 

    公益社団法人 日本アイソトープ協会

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各種コード

  • NII論文ID(NAID)
    10002684607
  • NII書誌ID(NCID)
    AN00351589
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00338303
  • NDL 記事登録ID
    4682123
  • NDL 雑誌分類
    ZM35(科学技術--物理学) // ZN36(科学技術--原子力工学・工業) // ZP2(科学技術--化学・化学工業--物理化学) // ZS45(科学技術--医学--放射線医学)
  • NDL 請求記号
    Z15-20
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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