Fundamental and Clinical Evaluation of a PIVKA-II Kit, “PIVKA-II IRMA 'Daiichi, <SUP>®</SUP>”
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- YOSHIKAWA Chiho
- Department of Radiology, Faculty of Medicine, Kyushu University
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- KUWABARA Yasuo
- Department of Radiology, Faculty of Medicine, Kyushu University
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- YAMAGUCHI Ikuko
- Department of Radiology, Faculty of Medicine, Kyushu University
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- YAGI Misako
- Department of Radiology, Faculty of Medicine, Kyushu University
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- NAGANO Fumiko
- Department of Radiology, Faculty of Medicine, Kyushu University
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- NAKAMURA Nobuko
- 九州大学医学部附属病院中央検査部
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- SASAKI Masayuki
- 九州大学医学部附属病院放射線科
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- YOSHIDA Tsuyoshi
- 九州大学医学部附属病院放射線科
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- NAKAGAWA Makoto
- 九州大学医学部附属病院放射線科
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- MASUDA Kouji
- 九州大学医学部附属病院放射線科
Bibliographic Information
- Other Title
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- PIVKA-II IRMA「第一」<SUP></SUP>の基礎および臨床的検討
- PIVKA-2 IRMA「第一」の基礎および臨床的検討
- PIVKA-2 IRMA ダイイチ ノ キソ オヨビ リンショウテキ ケントウ
- Fundamental and Clinical Evaluation of a PIVKA-II Kit, “PIVKA-II IRMA 'Daiichi, <SUP>®</SUP>”
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Abstract
We evaluated the characteristics and clinical efficacy of the“PIVKA-II IRMA‘Daiichi, ®”kit for estimating the serum PIVKA-II levels in hepatocellular carcinoma patients. Intraassay and interassay variances were within 10%. Recovery and dilution tests also gave satisfactory results. There was no significant effect of reaction time on PIVKA-II levels. However, PIVKA-II levels were significantly lower in heparinized plasma than those in serum and EDTA plasma. The cut-off level was determined as 40mAU/mL, mean +3SD of PIVKA-11 level in 84 normal control subjects. The sensitivity and specificity of“PIVKA-IIIRMA lsquo;Daiichi, ®”kit for hepatocellular carcinoma patients was 81; 6% and 82.4%, respectively. A significant correlation was observed between PIVKA-II levels measured by“PIVKA-II IRMA‘Daiichi, ®”kit and “EitestR Mono P II”EIA kit (r=979) . In conclusion, “PIV-KA-II IRMA‘Daiichi, ® kit is considered to be accurate and useful for measuring PIVKA-II levels in hepatocellular carcinoma patients.
Journal
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- RADIOISOTOPES
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RADIOISOTOPES 48 (3), 188-194, 1999
Japan Radioisotope Association
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Details 詳細情報について
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- CRID
- 1390282679133293952
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- NII Article ID
- 10002684607
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- NII Book ID
- AN00351589
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- ISSN
- 18844111
- 00338303
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- NDL BIB ID
- 4682123
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed