Comparative Activation Modes in Organic Chemistry. Pressure vs Hydrophobic Effects.

• Salem R. Ben

  Université de Sfax

• Jenner G.

  Institut de Chimie, Université Louis Pasteur

Bibliographic Information

Other Title

• Comparative Activation Modes in Organic

Abstract

The merits of two activation modes in organic synthesis are compared: pressure and physicochemical activation. The latter mode considers hydrophobic effects arising from aggregation of organic molecules in water. Both activation types stimulate the reactivity of addition reactions such as [4+2] cycloadditions, Michael additions and Baylis-Hillman reactions. However, the effect of water is complex and usually not predictable whereas high pressure proves to be an excellent activation mode. Combination of both activation processes can lead to convergent syntheses.

Journal

• The Review of High Pressure Science and Technology

  The Review of High Pressure Science and Technology 7 1268-1270, 1998

  The Japan Society of High Pressure Science and Technology

Keywords

• activation mode
• organic synthesis
• hydrophobic effects
• pressure

Details

• CRID: 1390282679358929920
• NII Article ID: 10002693675
• NII Book ID: AN10452913
• DOI: 10.4131/jshpreview.7.1268
• ISSN: 13481940
• ISSN: 0917639X
• NDL BIB ID: 4494211
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4494211
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed