Activity of Nucleic Acids and Peptides at High Pressure.

• Krzyzaniak Andrzej

  Institute of the Bioorganic Chemistry, Polish Academy of Sciences

• Jurczak Janusz

  Department of Chemistry, Warsaw University Institute of Organic Chemistry, Polish Academy of Sciences

• Porowski Sylwester

  High Pressure Research Center, Polish Academy of Sciences

• Barciszewski Jan

  Institute of the Bioorganic Chemistry, Polish Academy of Sciences

書誌事項

タイトル別名

• Activity of Nucleic Acids and Peptides

抄録

For last few years we have been interested in high pressure effects on biological molecules especially nucleic acids. We have found that DNA having consecutive pirymidine: purine nucleotide sequences change their conformation from Bto Z-form. Also synthetic oligoribonucleotides change their from A to Z, but at high pressure and in the presence of high salt concentration. Transfer ribonucleic acid specific for phenylalanine can be specifically aminoacylated at high pressure in the absence of aminoacyl-tRNA synthetase and ATP. tRNA charged at high pressure is a correct substrate for ribosomal protein synthesis and also catalyses peptide synthesis in vitro.

収録刊行物

• 高圧力の科学と技術

  高圧力の科学と技術 7 1303-1305, 1998

  日本高圧力学会

キーワード

• biological activity at high pressure
• nucleic acids
• peptides
• conformational equilibria

詳細情報

• CRID: 1390001204380526848
• NII論文ID: 10002693862
• NII書誌ID: AN10452913
• DOI: 10.4131/jshpreview.7.1303
• ISSN: 13481940
• ISSN: 0917639X
• NDL書誌ID: 4494221
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4494221
• 本文言語コード: en
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• 抄録ライセンスフラグ: 使用不可