脂質コーティングキトサン微粒子からのニコチンの制御放出特性

書誌事項

タイトル別名
  • Controlled-Release Behavior of Nicotine from Chitosan Microparticles Coated with Artificial Lipids.
  • シシツ コーティング キトサン ビリュウシ カラ ノ ニコチン ノ セイギョ

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抄録

Controlled-release behavior of nicotine from chitosan microparticles coated with two artificial lipids was investigated. These lipid coating chitosan microparticles can control the release rate of nicotine under zero-order kinetics for a long period as well as a wide range of release extents. Additionally, the release rates of nicotine significantly increased beyond 3437°C, possibly due to the phase transition phenomena of artificial lipid coatings. These lipid coating chitosan microparticles may be applied to transdermal nicotine patches for controlled-release as well as long preservation period.

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