超臨界流体の基礎と応用　超臨界流体によるクロマトグラフィー分離

• 山本 修一

  山口大学工学部応用化学工学科

書誌事項

タイトル別名

• Supercritical Fluid Chromatographic Separation.

抄録

The relationships between the plate height HETP and the linear mobile phase velocity u in supercritical fluid chromatography (SFC) were investigated over a wide range of experimental conditions (pressure p = 8. 5 ∼ 15 MPa, temperature T = 35 ∼ 45°C) with carbon dioxide as the mobile phase. When the HETP - u curves were converted into the dimensionless variables h = HETP/d_p and ν = ud_p/D_m, the curves were similar regardless of the pressure, the temperature and the state of the mobile phase. The distribution coefficient K decreased with increasing T and/or p. The K values were correlated to the mobile phase density. A linear increase of the pressure was applied to elute the sample from the column. The result was simulated by a chromatography model with the isobar chromatography data. These results have shown that the separation behavior of SFC at low sample loadings can be predicted by ordinary liquid chromatography models. Further research should be done for the prediction of the separation behavior at overloaded conditions.

収録刊行物

• 高圧力の科学と技術

  高圧力の科学と技術 5 (2), 78-83, 1996

  日本高圧力学会

キーワード

• supercritical fluid
• chromatography
• diffusion coefficient
• axial dispersion
• HETP
• distribution coefficient

詳細情報

• CRID: 1390282679357008896
• NII論文ID: 10002848051
• NII書誌ID: AN10452913
• DOI: 10.4131/jshpreview.5.78
• ISSN: 13481940
• ISSN: 0917639X
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可