Recovery of Deinococcus radiodurans from radiation damage was enhanced under microgravity.

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  • Kobayashi Yasuhiko
    Biotechnology Laboratory, Takasaki Radiation Chemistry Research Establishment, Japan Atomic Energy Research Institute, 1233 Watanuki-machi, Gunma 370- 12, Japan.
  • Kikuchi Masahiro
    Biotechnology Laboratory, Takasaki Radiation Chemistry Research Establishment, Japan Atomic Energy Research Institute, 1233 Watanuki-machi, Gunma 370- 12, Japan.
  • Nagaoka Shunji
    National Space Development Agency of Japan, 1- 1, Sengen 2-chome, Tsukuba 305, Japan
  • Watanabe Hiroshi
    Biotechnology Laboratory, Takasaki Radiation Chemistry Research Establishment, Japan Atomic Energy Research Institute, 1233 Watanuki-machi, Gunma 370- 12, Japan.

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  • Recovery of Deinococcus radiodurans fro

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Abstract

Effect of microgravity on recovery of bacterial cells from radiation damage was examined on the IML-2 mission in 1994 using extremely radioresistant bacterium Deinococcus radiodurans. The cells were lyophilized and exposed to 60Co γ-rays with doses 2 to 12 kGy before the space flight. At the end of the mission, the cells were mixed on board with liquid nutrient medium to allow the cells to start recovery process from the radiation damage. Afterwards the cells were stored at 4°C until landing. The influence of cosmic radiation was negligible, because total absorbed dose of space radiation measured during the mission was less than 2 mGy and this bacterium does not decrease its viability after both γ-rays and high-LET heavy charged particles irradiation with doses up to 5 kGy. The survival of the cells incubated in space increased significantly compared with the ground controls, suggesting that the recovery of this bacterium from radiation damage was enhanced under microgravity.

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