充填層型固定化酵素反応器のみかけの速度パラメーターへの多孔性担体内の不均一活性分布の影響

書誌事項

タイトル別名
  • Effect of Nonuniform Activity Distribution in a Porous Support on Apparent Kinetic Parameters of a Packed-Bed Immobilized Enzyme Reactor.
  • ジュウテンソウガタ コテイカ コウソ ハンノウキ ノ ミカケ ノ ソクド パラ

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The effect of nonuniform activity distribution in a porous support on the apparent kinetic parame-ters, Vmapp and Kmapp, of a packed-bed immobilized enzyme reactor has been theoretically investigated. Vmapp and Kmapp increase with the increase of external diffusional resistance, regardless of the type ofnonuniform activity distribution. As the external diffusional resistance becomes significant, the apparent kinetic parameters became less dependent on the substrate concentration at the reactor inlet. Like the case of diffusional resistance or electrostatic field, the nonuniform activity distribution had a significant effect on Kmapp.

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