｀１２５´Ｉ動物実験における安全取扱

• 西槇 俊之

  北里大学医学部RI系

• 酒井 康弘

  北里大学医学部解剖学

• 古舘 専一

  北里大学医学部実験動物学

書誌事項

タイトル別名

• Safety Handling of 125I in Animal Experiments.
• 125I ドウブツ ジッケン ニ オケル アンゼン トリアツカイ

抄録

Isotope ¹²⁵I in animal experiments is used for several purposes. One major problem with using ¹²⁵I is to handle it extremely carefully. The careful handling is required when using ¹²⁵I in animal experiments because of its higher evaporation and difficulty for sealing. When conducting animal experiments while using ¹²⁵I, we have encountered several serious problems but have devised new techniques and methods for a long time. In this paper, we will describe the safety handling for requirements based on our experiments. The newly devised safety handling procedures are the following : (1) a device for protecting isotope contamination during the preparation of the injectable solution, (2) collection method of airborne radioactivity from the animals that were injected, (3) enhancing the method for autoradiography of the whole body, (4) finding of elusion of ¹²⁵I from the tissues during fixative process, (5) estimation of the exposed time for light microscopic autoradiography.

収録刊行物

• ＲＡＤＩＯＩＳＯＴＯＰＥＳ

  ＲＡＤＩＯＩＳＯＴＯＰＥＳ 45 (10), 626-630, 1996

  公益社団法人 日本アイソトープ協会

キーワード

• iodine-125
• safety handling
• animal experiment
• autoradiography

詳細情報

• CRID: 1390001204152238976
• NII論文ID: 130004382858
• NII論文ID: 10003720509
• NII書誌ID: AN00351589
• DOI: 10.3769/radioisotopes.45.626
• ISSN: 18844111
• ISSN: 00338303
• NDL書誌ID: 4055913
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4055913
• Web Site: http://www.jstage.jst.go.jp/article/radioisotopes1952/45/10/45_10_626/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1997041970
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可