Control of the availability of exogenous 5-aminolevulinic acid in Escherichia coli

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抄録

We observed novel phenomena on the growth of a <i>hemA</i> deletion mutant (H500) of <i>Escherichia coli</i>: First, H500 cells grown in rich medium required an increased amount of exogenous 5-aminolevulinic acid (ALA) for normal growth, as compared with cells grown in poor medium. Second, H500 cells grown with an insufficient supply of ALA had a prolonged lag phase but relatively normal growth during the logarithmic phase. An increased requirement of exogenous ALA in rich media was due to an impermeability of the cells to ALA, resulting in a reduced ability to synthesize porphyrins. The latter could be also explained by change in permeability that was repressed under heme-deficient conditions.<br>

収録刊行物

  • Genes & genetic systems

    Genes & genetic systems 71(4), 237-241, 1996-08

    The Genetics Society of Japan

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各種コード

  • NII論文ID(NAID)
    10003760073
  • NII書誌ID(NCID)
    AA11077421
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13417568
  • NDL 記事登録ID
    4163727
  • NDL 雑誌分類
    ZR1(科学技術--生物学)
  • NDL 請求記号
    Z53-W539
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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