Molecular identification of the active ninja retrotransposon and the inactive aurora element in Drosophila simulans and D. melanogaster

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How transposable elements evolve is a key facet in understanding of spontaneous mutation and genomic rearrangements in various organisms. One of the best ways to approach this question is to study a newly evolved transposable element whose presence is restricted to a specific population or strain. The retrotransposons <i>ninja</i> and <i>aurora</i> may provide insights into the process of their evolution, because of their contrasting characteristics, even though they show high sequence identity. The <i>ninja</i> retrotransposon was found in a <i>Drosophila simulans</i> strain in high copy number and is potent in transposition. On the other hand, <i>aurora</i> elements are distributed widely among the species belonging to the <i>Drosophila melanogaster</i> species complex, but are immobile at least in <i>D. melanogaster</i>. In order to distinguish the two closely resembled retrotransposons by molecular means, we determined and compared DNA sequence of the elements, and identified characteristic internal deletions and nucleotide substitutions in 5'-long terminal repeats (LTR). Analyses of the structure of <i>ninja</i> homologs and LTR sequences amplified from both genomic and cloned DNA revealed that the actively transposable <i>ninja</i> elements were present only in <i>D. simulans</i> strains, but inactive <i>aurora</i> elements exist in both <i>D. melanogaster</i> and <i>D. simulans</i>.<br>

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  • Genes & genetic systems

    Genes & genetic systems 73(6), 385-396, 1998-12-01

    The Genetics Society of Japan

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各種コード

  • NII論文ID(NAID)
    10003763456
  • NII書誌ID(NCID)
    AA11077421
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13417568
  • NDL 記事登録ID
    4681983
  • NDL 雑誌分類
    ZR1(科学技術--生物学)
  • NDL 請求記号
    Z53-W539
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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