Helical Stereoregular Artificial Glycoconjugate Polymers Based on Poly (phenylacetylene) Backbone : Synthesis and Molecular Recognition with Lectin

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著者

    • MATSUURA Kazunori
    • Department of Molecular Design and Department of Biotechnology, Graduate School of Engineering, Nagoya University
    • FURUNO Shi-ichi
    • Department of Molecular Design and Department of Biotechnology, Graduate School of Engineering, Nagoya University
    • KOBAYASHI Kazukiyo
    • Department of Molecular Design and Department of Biotechnology, Graduate School of Engineering, Nagoya University

抄録

Stereoregular poly(phenylacetylene)s bearing pendant lactose and cellobiose moiety were synthesized by polymerization of β-N-glycosylated 4-ethynylbenzamides with [Rh(nbd)Cl]<SUB>2</SUB> (nbd=norbornadiene) as initiator. The glycoconjugate polymer possessed alternating double bond backbone with cis-transoidal regioregularity and helical conformation. Inhibition assay of hemagglutination revealed that galactose-specific lectin efficiently bound to the stereoregular helical glycopolymer bearing lactose, but the binding was not so strong as that of the corresponding flexible glycoconjugate polystyrene.

収録刊行物

  • Chemistry letters

    Chemistry letters 1998(8), 847-848, 1998-08-05

    The Chemical Society of Japan

参考文献:  17件中 1-17件 を表示

  • <no title>

    LEE Y. C.

    Neoglycoconjugates : Preparation and Applications, 1994

    被引用文献8件

  • <no title>

    FURUIKE T.

    Macromolecules 28, 7241, 1995

    被引用文献5件

  • <no title>

    ZANINI D.

    J. Am. Chem. Soc. 119, 2088, 1997

    被引用文献10件

  • <no title>

    MANNING D. D.

    J. Am. Chem. Soc. 119, 3161, 1997

    被引用文献5件

  • <no title>

    CHOI S.

    J. Am. Chem. Soc. 119, 4103, 1997

    被引用文献3件

  • <no title>

    KOBAYASHI K.

    Polym. J. 17, 567, 1985

    被引用文献14件

  • <no title>

    KOBAYASHI K.

    Macromolecules 30, 2016, 1997

    被引用文献11件

  • <no title>

    KOBAYASHI K.

    J. Carbohydr. Chem. 13, 753, 1994

    被引用文献10件

  • <no title>

    KOBAYASHI K.

    Carbohydr. Res. 242, 161, 1993

    被引用文献9件

  • <no title>

    KOBAYASHI K.

    Biochem. Biophys. Acta 1336, 997, 1997

    被引用文献2件

  • <no title>

    YAMAGUCHI M.

    Chem. Lett. 1992, 2261

    被引用文献5件

  • <no title>

    AOKI T.

    Chem. Lett. 1993, 2009

    被引用文献8件

  • <no title>

    KISHIMOTO Y.

    Macromolecules 28, 6662, 1995

    被引用文献9件

  • <no title>

    YASHIMA E.

    Macromolecules 28, 4184, 1995

    被引用文献13件

  • <no title>

    YASHIMA E.

    J. Am. Chem. Soc. 119, 6345, 1997

    被引用文献20件

  • <no title>

    AVIGARD G.

    J. Biol. Chem. 237, 2736, 1962

    被引用文献2件

  • <no title>

    LIKHOSHERSTOV L. M.

    Carbohydr. Res. 146, C1-C5, 1986

    被引用文献5件

各種コード

  • NII論文ID(NAID)
    10004484891
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    03667022
  • データ提供元
    CJP書誌  J-STAGE 
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