Toward Synthesis of Novel C-glycoprotein from Human RNase ; Unexpected Stereochemistry of Epoxide Opening Reaction by Organolithium Reagents in the Presence of Lewis Acid
A nucleophilic attack reaction to 1,2-anhydro-β-D-manno-pyranose by indole derived organolithium reagents in the presence of BF<SUB>3</SUB>·OEt<SUB>2</SUB> afforded isomers of C-aryl glycoside corresponds to the basic skeleton of C-linked mannosyl tryptophan, which is recently identified in human RNase.
- Chemistry letters
Chemistry letters 1998(9), 919-920, 1998-09-05
The Chemical Society of Japan