Evidence for Spontaneous Cycloaromatization of Nine-Membered Monocyclic Enediyne
Treatment of 2,2-dimethyl-6-nonene-4,8-diynal (2) with CeCl<SUB>3</SUB>/LiN(TMS)<SUB>2</SUB> at −5∼25°C gave 2,2-dimethyl-1-indanol (3) in a moderate yield. In the present study, acyclic (Z)-enediyne aldehyde (2) was cyclized to afford a nine-membered monocyclic enediyne (7), which cycloaromatized spontaneously at room temperature.
- Chemistry letters
Chemistry letters 1998(9), 959-960, 1998-09-05
The Chemical Society of Japan