Synthesis of Carboxylic Acids through the Formation of C - C Bond between Saturated Hydrocarbons and CO in the Presence of Mg/K_2S_2O_8/TFA System
Magnesium powder (Mg) promoted the carboxylation reaction of saturated hydrocarbons with carbon monoxide (CO) in the presence of potassium peroxodisulfate (K<SUB>2</SUB>S<SUB>2</SUB>O<SUB>8</SUB>) in trifluoroacetic acid (TFA) to yield the corresponding carboxylic acids and alkyl trifluoroacetates. About 80% conversion of cyclohexane was achieved when 5 mmol of magnesium, 5 mmol of potassium peroxodisulfate, 3 mL of TFA, 1 mmol of cyclohexane, 50 atm of CO were used at 80 °C for 30 h.
- Chemistry letters
Chemistry letters 1999(6), 449-450, 1999-06-05
The Chemical Society of Japan