A Unique Chelating Effect of Sc(OTf)_3 to Organofluorine Compounds
The scandium trifluoromethanesulfonate-catalyzed cleavage of acetate bearing two or three fluorine atoms at a position β to an acetoxy group proceeds exceptionally rapidly. The high efficiency of the hydrolysis is caused by a chelating effect of scandium with the fluorine atoms and an acetate moiety.
- Chemistry letters
Chemistry letters 1999(6), 459-460, 1999-06-05
The Chemical Society of Japan