A Unique Chelating Effect of Sc(OTf)_3 to Organofluorine Compounds
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The scandium trifluoromethanesulfonate-catalyzed cleavage of acetate bearing two or three fluorine atoms at a position β to an acetoxy group proceeds exceptionally rapidly. The high efficiency of the hydrolysis is caused by a chelating effect of scandium with the fluorine atoms and an acetate moiety.
- Chemistry Letters
Chemistry Letters 1999(6), 459-460, 1999-06-05
The Chemical Society of Japan