Calcium Phosphate Formation on Highly-oriented Collagen Fibrils

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  • Yoshiyuki Yokogawa
    National Industrial Research Institute of Nagoya1-1 Hirate-cho, Kita-ku, Nagoya
  • Fukue Nagata
    National Industrial Research Institute of Nagoya1-1 Hirate-cho, Kita-ku, Nagoya
  • Motohiro Toriyama
    National Industrial Research Institute of Nagoya1-1 Hirate-cho, Kita-ku, Nagoya

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<jats:title>Abstract</jats:title> <jats:p>Calcium phosphate formation on collagen fibrils was studied. Collagen fibrils deposited from a collagen solution were insolubilized by UV-irradiation. The collagen fibrils looked to be precipitated and arranged in one direction in a narrow space due to convection stream from bottom to top of test tube. Highly-oriented collagen fibrils precipitated were soaked in simulated body fluid (SBF) solution at 36.5 °C. After immersion of SBF solution at 36.5 °C for 3 days, calcium phosphate was formed on insolubilized collagen fibrils. In contrast, no calcium phosphate was formed on collagen fibrils without insolubilization treatment.</jats:p>

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  • Chemistry Letters

    Chemistry Letters 28 (6), 527-528, 1999-06-01

    Oxford University Press (OUP)

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