カテコール2,3-ジオキシゲナーゼ(メタピロカテカーゼ)の結晶構造 [in Japanese] X-ray Crystal Structure of Catechol 2,3-Dioxygenase (Metapyrocatechase) [in Japanese]
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The three-dimensional structure of catechol 2, 3-dioxygenases (metapyrocatechase, MPC), which catalyzes the proximal extradiol cleavage reaction of catechol and 3- or 4-substituted catechol, has been determined at 2.8Å resolution. The enzyme is a homotetramer with non-crystallographic 222 symmetry and each subunit is folded into two similar domains. The active site structure reveals a distorted tetrahedral Fe (II) site coordinated by three endogenous ligands (His 153, His214, and G1u265) and an acetone molecule.
X-RAYS 42(4), 361-366, 2000-08-31
The Crystallographic Society of Japan