Acceleration Effects of Phosphine Ligands in the Nickel Catalyzed Methylation of Aldehydes Using Trimethylaluminum
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A nickel catalyzed methylation of aldehydes was conducted successfully using trimethylaluminum as an alkylation reagent. In the presence of a phosphine or phosphite ligand, the reaction was considerably accelerated to give the methylation product in good yields.
- Chemistry Letters
Chemistry Letters 1998(10), 1033-1034, 1998-10-05
The Chemical Society of Japan