Uniform-sized Molecularly Imprinted Polymers for β-Estradiol
A uniform-sized molecularly imprinted polymer (MIP) for β-estradiol has been prepared using 4-vinylpyridine and ethylenedimethacrylate as a functional monomer and cross-linker, respectively. The molecular recognition properties of the MIP were evaluated by HPLC using a mixture of phosphate buffer and acetonitrile as the eluent. The MIP showed the highest selectivity for β-estradiol. The MIP could efficiently separate estrogens from other steroids such as testosterone and corticosterone, and could separate estrogens one another.
- Chemistry letters
Chemistry letters 1998(11), 1089-1090, 1998-11-05
The Chemical Society of Japan