Uniform-sized Molecularly Imprinted Polymers for β-Estradiol

  • Jun Haginaka
    Faculty of Pharmaceutical Sciences, Mukogawa Women’s University
  • Haruyo Sanbe
    Faculty of Pharmaceutical Sciences, Mukogawa Women’s University

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<jats:title>Abstract</jats:title> <jats:p>A uniform-sized molecularly imprinted polymer (MIP) for β-estradiol has been prepared using 4-vinylpyridine and ethylenedimethacrylate as a functional monomer and cross-linker, respectively. The molecular recognition properties of the MIP were evaluated by HPLC using a mixture of phosphate buffer and acetonitrile as the eluent. The MIP showed the highest selectivity for β-estradiol. The MIP could efficiently separate estrogens from other steroids such as testosterone and corticosterone, and could separate estrogens one another.</jats:p>

収録刊行物

  • Chemistry Letters

    Chemistry Letters 27 (11), 1089-1090, 1998-11-01

    Oxford University Press (OUP)

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