Synthesis of 4-Hydroxy-2-cyclopentenone Derivatives by [3+2] Annulation of β-Heteroatom-Substituted Acryloylsilanes and Lithium Enolate of Methyl Ketones
Access this Article
Search this Article
The [3 + 2] annulation using β-[2-(pyridyl)thio] and β,β-dichloro derivatives of acryloylsilane and the lithium enolate of methyl ketones successfully proceeded to afford 4-alkyl-4-hydroxy-3-(2-pyridylthio)cyclopentanone and 4-alkyl-3-chloro-4-hydroxy-2-cyclopentenone, respectively.
- Chemistry Letters
Chemistry Letters 1998(11), 1157-1158, 1998-11-05
The Chemical Society of Japan