Fabrication of PLGA-Collagen Hybrid Sponge

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著者

    • CHEN Guoping
    • 3D Tissue Engineering Group, National Institute for Advanced Interdisciplinary Research
    • USHIDA Takashi
    • 3D Tissue Engineering Group, National Institute for Advanced Interdisciplinary Research
    • TATEISHI Tetsuya
    • 3D Tissue Engineering Group, National Institute for Advanced Interdisciplinary Research

抄録

A hybrid sponge of biodegradable poly(DL-lactic-co-glycolic acid) (PLGA) and collagen was fabricated by forming microsponges of collagen in the pores of PLGA sponge. Observation of the hybrid sponge by scanning electron microscopy (SEM) showed that microsponges of collagen with interconnected pore structures were formed. The hybrid structure was further confirmed by detecting elemental nitrogen using scanning electron microscopy-electron probe microanalysis (SEM-EPMA). Elemental nitrogen was detected in the microsponges of collagen and on the pore surfaces of PLGA, but not in the cross-sections of PLGA regions. These results indicate that microsponges of collagen were formed in the pores of the PLGA sponge and that the pore surfaces were also coated with collagen.

収録刊行物

  • Chemistry letters

    Chemistry letters 1999(7), 561-562, 1999-07-05

    The Chemical Society of Japan

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各種コード

  • NII論文ID(NAID)
    10004701501
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    OTR
  • ISSN
    03667022
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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