<i>α</i>–<i>β</i> Structural Transition of Short Oligopeptides by Water/Organic Solvent Titration

DOI PDF 被引用文献2件 参考文献28件
  • Naoki Sugimoto
    Department of Chemistry, Faculty of Science, Konan University8-9-1 Okamoto, Higashinada-ku, Kobe
  • Jin Zou
    Department of Chemistry, Faculty of Science, Konan University8-9-1 Okamoto, Higashinada-ku, Kobe
  • Hideki Kazuta
    Department of Chemistry, Faculty of Science, Konan University8-9-1 Okamoto, Higashinada-ku, Kobe
  • Daisuke Miyoshi
    Department of Chemistry, Faculty of Science, Konan University8-9-1 Okamoto, Higashinada-ku, Kobe

この論文をさがす

抄録

<jats:title>Abstract</jats:title> <jats:p>Designed two peptides, Ac-Trp-Lys-Ala13-Lys-NH2 and Ac-Trp-Lys-Ala15-Lys-NH2 were synthesized by utilizing natural L-amino acids and were capable of performing a structural transition from β-sheet to α-helix. The α–β transition of the designed peptides was induced by interstrand hydrophobic interaction. This shows that our designed peptides may be an model system for the elucidation of misfolding and transformation mechanism of pathogenic proteins.</jats:p>

収録刊行物

  • Chemistry Letters

    Chemistry Letters 28 (7), 637-638, 1999-07-01

    Oxford University Press (OUP)

被引用文献 (2)*注記

もっと見る

参考文献 (28)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ