Microbial 7-OH Epimerisation of Bile Acids
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The microbial 7-OH epimerisation of cholic and chenodeoxycholic acids with <I>Xanthomonas maltophilia</I> CBS 827.97 to ursocholic and ursodeoxycholic acids with scarsity of oxygen is described. With normal pressure of oxygen the 7-ketocholic and the 7-ketochenodeoxycholic acids are obtained. No biotransformation is achieved in anaerobic conditions.
- Chemistry Letters
Chemistry Letters 1999(7), 693-694, 1999-07-05
The Chemical Society of Japan