In situ Monitoring of Poly(L-glutamine)-Bound dsDNA Selection on a Quartz-Crystal Microbalance

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著者

    • FURUSAWA Hiroyuki
    • Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology
    • EBARA Yasuhito
    • Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology
    • OKAHATA Yoshio
    • Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

抄録

We applied a highly sensitive quartz-crystal microbalance as a device of dsDNA <I>in vitro</I> selection. When poly((<FONT SIZE=-2>L</FONT>-glutamine)-immobilized QCM was employed, both the selection and evaluation processes could be monitored <I>in situ</I> as mass changes, and the dsDNAs having the continuous sequences of 3-5 AT base-pairs were selected after the 4<SUP>th</SUP> cycle from a random dsDNA pool.

収録刊行物

  • Chemistry letters

    Chemistry letters 1999(8), 823-824, 1999-08-05

    The Chemical Society of Japan

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各種コード

  • NII論文ID(NAID)
    10004703509
  • NII書誌ID(NCID)
    AA00603318
  • 本文言語コード
    ENG
  • 資料種別
    OTR
  • ISSN
    03667022
  • データ提供元
    CJP書誌  J-STAGE 
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