Highly Enantioselective Cyclopropanation of Styrenes with Diazoacetates Catalyzed by Optically Active β-Ketoiminato Cobalt(II)Complexes
The highly enantioselective cyclopropanation of styrenes with diazoacetates was achieved using reasonably designed β-ketoiminato cobalt(II) complex catalysts. In the presence of optically active cobalt(II) complexes derived from optically active 1,2-(2,4,6-trimethylphenyl)-1,2-ethylenediamine, the cyclopropanation of styrene with methyl, ethyl, and <I>tert</I>-butyl diazoacetates proceeded to afford the corresponding cyclopropanecarboxylates with 94-96% ee.
- Chemistry letters
Chemistry letters 1999(12), 1345-1346, 1999-12-05
The Chemical Society of Japan