Random fluidic self-assembly法による生体材料の固定化 Immobilization of Biomaterial by Rondam Fluidic Self-Assembly Method

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We propose a novel method for individual immobilization of biomaterial for biosensor application. Various kinds of biomaterial were first immobilized on certain supports such as glass beads or microfabricated metal particles of which size is almost the same as the size of transducer element. Then the suspension mixture of the various support was arranged on the transducer array by the fluidic self-assembly method at random. Glass beads immobilized with glucose oxidase and/or peroxidase were successfully arranged by this method using gravity, as a short-range force required in self-assembly. The beads gave chemiluminescence with the addition of luminol and its substrate. The metal particles consisted of nickel and/or gold layers formed by electroplating and evaporation on a photolithographically patterned chip. The coin-shaped particles were arranged on a nickel dot array by magnetic force interaction as the short-range force. The direction of binding of the particles were also controllable using the multilayer structure.

収録刊行物

  • 電気学会論文誌. E, センサ・マイクロマシン準部門誌 = The transactions of the Institute of Electrical Engineers of Japan. A publication of Sensors and Micromachines Society  

    電気学会論文誌. E, センサ・マイクロマシン準部門誌 = The transactions of the Institute of Electrical Engineers of Japan. A publication of Sensors and Micromachines Society 119(8), 436-442, 1999-08 

    The Institute of Electrical Engineers of Japan

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各種コード

  • NII論文ID(NAID)
    10004834246
  • NII書誌ID(NCID)
    AN1052634X
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    13418939
  • NDL 記事登録ID
    4816622
  • NDL 雑誌分類
    ZN31(科学技術--電気工学・電気機械工業)
  • NDL 請求記号
    Z16-B380
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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