Human Recombinant Activin Induces Proliferation of Spermatogonia in vitro in the Japanese Eel Anguilla japonica
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- Miura Takeshi
- Department of Biology, Faculty of Fisheries, Hokkaido University
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- Miura Chiemi
- Department of Biology, Faculty of Fisheries, Hokkaido University
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- Yamauchi Kohei
- Department of Biology, Faculty of Fisheries, Hokkaido University
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- Nagahama Yoshitaka
- Laboratory of Reproductive Biology, Department of Developmental Biology, National Institute for Basic Bilolty
書誌事項
- タイトル別名
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- Human Recombinant Activin Induces Proliferation of Spermatogonia <i>in vitro</i> in the Japanese Eel <i>Anguilla japonica</i>
- Human Recombinant Activin Induces Proli
この論文をさがす
抄録
Activin, a member of the transforming growth factor-β superfamily, has recentlybeen isolated from eel testicular cDNA library. Using an in vitro testicular organ culture system, we investigated the effect of human recombinant activin A and B in eel spermatogenesis. Addition of human recombinant activin A and B (10 ng and 100 ng/ml) to the culture medium induced proliferation of spermatogonia within 15 days in the same manner as addition of 11-ketotestosterone (10 ng/ml) for positive control. In cultured testes without activins, however, the proliferation of spermatogoniawas not observed. Although it is necessary to investigate the eel's own activin A and B protein, these results suggest the possibility that activin induces initiation of spermatogenesis in Japanese eel.
収録刊行物
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- Fisheries science
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Fisheries science 61 (3), 434-437, 1995
公益社団法人 日本水産学会
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詳細情報 詳細情報について
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- CRID
- 1390001204430413312
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- NII論文ID
- 130003902693
- 10004862134
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- NII書誌ID
- AA10993718
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- COI
- 1:CAS:528:DyaK2MXmsFert7Y%3D
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- NDL書誌ID
- 3642640
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- ISSN
- 09199268
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可