Production of Monohydroxy Derivatives from Highly Unsaturated Fatty Acids in the Gills of Red Sea Bream Pagrus major

DOI Web Site Web Site 被引用文献1件 参考文献40件
  • Iijima Noriaki
    Faculty of Applied Biological Science, Hiroshima University
  • Hada Takahiko
    Faculty of Applied Biological Science, Hiroshima University Institute for BioMedical Research, Teijin Pharmaceutical Ltd.
  • Kayama Mitsu
    Faculty of Applied Biological Science, Hiroshima University Faculty of Engineering, Fukuyama University

書誌事項

タイトル別名
  • Production of Monohydroxy Derivatives from Highly Unsaturated Fatty Acids in the Gills of Red Sea Bream <i>Pagrus major</i>
  • Production of Monohydroxy Derivatives f

この論文をさがす

抄録

12-Hydroxyeicosatetraenoic acid and 15-hydroxyeicosatetraenoic acid were produced as major and minor monohydroxylated products in a microsome fraction, when [1-14C]arachidonic acid was incubated with the microsome or cytosol fraction prepared from frozen stored gill tissue of red sea bream Pagrus major. The endogenousproducts extracted from the microsome fraction of red sea bream gill were isolatedby high performance liquid chromatography and identified as 12-hydroxyeicosatetraenoic acid, 12-hydroxyeicosapentaenoic acid and 14-hydroxydocosahexaenoic acid by ultraviolet absorption spectrometry and gas chromatography-mass spectrometry.These data suggest that arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid are converted to their monohydroxy derivatives via the hydroperoxides bythe action of 12-lipoxygenase-like enzyme, which is distributed in the microsomesof red sea bream gill.

収録刊行物

被引用文献 (1)*注記

もっと見る

参考文献 (40)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ