Molecular Analysis of Complement Regulatory Protein-Like cDNA from the Japanese Flounder <i>Paralichthys olivaceus</i>
-
- Katagiri Takayuki
- Laboratory of Genetics and Biochemistry, Tokyo University of Fisheries
-
- Hirono Ikuo
- Laboratory of Genetics and Biochemistry, Tokyo University of Fisheries
-
- Aoki Takashi
- Laboratory of Genetics and Biochemistry, Tokyo University of Fisheries
Bibliographic Information
- Other Title
-
- Molecular Analysis of Complement Regulatory Protein-Like cDNA from the Japanese Flounder Paralichthys olivaceus
- Molecular Analysis of Complement Regula
Search this article
Abstract
We cloned and analyzed a complement regulatory protein cDNA (designated HCRF) from the Japanese flounder Paralichthys olivaceus. The length of the cDNA obtained was 1662 bp. The predicted translation product represents a protein of 453 amino acids which displays a putative hydrophobic leader sequence. There were 7 short consensus repeats (SCRs) which are closely related to those of the previously described SBP1 and SBCFR-1 of complement regulatory plasma proteins of barred sand bass Paralabrax neblifer. The SCRs of HCRF, SBP1, and SBCFR-1 constitute 7, 17, and 3 domains, respectively. SCR domains Nos. 2 to 7 of HCRF resembled domains Nos. 12 to 17 of SBP1. SCR domains Nos. 6 and 7 of HCRF also closely resembled domains Nos. 2 and 3 of SBCFR-1, respectively.<br> The expression of the complement regulatory protein-like mRNA in flounder liver was demonstrated by Northern blot hybridization.
Journal
-
- Fisheries science
-
Fisheries science 64 (1), 140-143, 1998
The Japanese Society of Fisheries Science
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282679406516096
-
- NII Article ID
- 130003742118
- 10004873385
-
- NII Book ID
- AA10993718
-
- NDL BIB ID
- 4406518
-
- ISSN
- 09199268
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed