Comparison of the Amino Acid Sequence and Phylogenetic Analysis of the Peplomer, Integral Membrane and Nucleocapsid Proteins of Feline, Canine and Porcine Coronaviruses

• MOTOKAWA Kenji

  Department of Veterinary Infectious Diseases, School of Veterinary Medicine and Animal Sciences, Kitasato University

• HOHDATSU Tsutomu

  Department of Veterinary Infectious Diseases, School of Veterinary Medicine and Animal Sciences, Kitasato University

• HASHIMOTO Hiroshi

  Department of Virology, Center of Basic Research, The Kitasato Institute

• KOYAMA Hiroyuki

  Department of Veterinary Infectious Diseases, School of Veterinary Medicine and Animal Sciences, Kitasato University

抄録

Complete nucleotide sequences were determined by cDNA cloning of peplomer (S), integral membrane (M) and nucleocapsid (N) genes of feline infectious peritonitis virus (FIPV) type I strain KU-2, UCD1 and Black, and feline enteric coronavirus (FECV) type II strain 79-1683. Only M and N genes were analyzed in strain KU-2 and strain 79-1683, which still had unknown nucleotide sequences. Deduced amino acid sequences of S, M and N proteins were compared in a total of 7 strains of coronaviruses, which included FIPV type II strain 79-1146, canine coronavirus (CCV) strain Insavc-1 and transmissible gastroenteritis virus of swine (TGEV) strain Purdue. Comparison of deduced amino acid sequences of M and N proteins revealed that both M and N proteins had an identity of at least 90% between FIPV type I and type II. The phylogenetic tree of the M and N protein-deduced amino acid sequences showed that FIPV type I and type II form a group with FECV type II, and that these viruses were evolutionarily distant from CCV and TGEV. On the other hand, when the S protein-deduced amino acid sequences was compared, identity of only about 45% was found between FIPV type I and type II. The phylogenetic tree of the S protein-deduced amino acid sequences indicated that three strains of FIPV type I form a group, and that it is a very long distance from the FIPV type II, FECV type II, CCV and TGEV groups.

収録刊行物

• Microbiology and immunology

  Microbiology and immunology 40 (6), 425-433, 1996-06-20

  財団法人 学会誌刊行センター

キーワード

• Feline infectious peritonitis virus
• Feline enteric coronavirus
• Amino acid sequence

詳細情報

• CRID: 1573105974092077952
• NII論文ID: 10004893049
• NII書誌ID: AA00738350
• ISSN: 03855600
• Web Site: http://chemport.cas.org/cgi-bin/sdcgi?APP=ftslink&action=reflink&origin=jstage2&version=1.0&coi=1:CAS:528:DyaK28Xkt1Cms74%3D&md5=cb2fe4a20758c12a56d2507f0cf6a0cf
• Web Site: https://search.jamas.or.jp/link/ui/1997041369
• 本文言語コード: en
• データソース種別:
  • CiNii Articles