Nosocomial Diarrhoea in the Elderly Due to Enterotoxigenic Clostridium perfringens

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To diagnose sporadic diarrhoea due to <I>Clostridium perfringens</I> infection, faecal specimens from elderly patients were examined directly for <I>C. perfringens</I> enterotoxin using reverse passive latex agglutination assay, and then cultured for this organism. <I>C. perfringens</I> isolates from those samples were grouped by slide agglutination and by pulsed-field gel electrophoresis (PFGE). Fifty of the 60 isolates agglutinated with newly raised antiserum WX2 and 38 shared the same genomic PFGE pattern. Characteristics of the epidemics and experimental data suggest that the diarrhoea was caused by a nosocomial spread of <I>C. perfringens</I>, and not by a food-borne outbreak.

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  • Microbiology and immunology  

    Microbiology and immunology 40(10), 767-771, 1996-10-20 

    Center For Academic Publications Japan

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