書誌事項
- タイトル別名
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- A Case of NIDDM with Transition to IDDM by Interferon Administration for the Treatment of Chronic Hepatitis C.
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A patient with chronic hepatitis C associated with NIDDM was treated with interferon. His ICA changed to positive and transtition to IDDM with a marked increase in blood sugar was found.<BR>This patient was a 35-year-old man who was found to have liver dysfunction and diabetes at the age of 33. In October 1992, he was hospitalized with anorexia and reduced body weight as his chief complaints. After dietary therapy and transitional insulin therapy, he was administered an oral antidiabetic agent (40 mg/day ofgliclazide). When his blood sugar was well controlled, a liver biopsy was performed and interferon treatment was started. From the 3rd day of interferon administration, marked increases in urinary sugar excretion and blood sugar level were observed. Furthermore, insulin secretion was reduced, and ICA, which was not seen before interferon administration, appeared.<BR>This case suggests there is a possibility that blood sugar will increase through the mechanism of appearance of ICA when interferon is administered to patients with chronic active hepatitis C associated with or without glucose tolerance disorders, and that special attention should be given to patients with glucose tolerance disorders.
収録刊行物
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- 糖尿病
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糖尿病 38 (6), 455-460, 1995
一般社団法人 日本糖尿病学会
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詳細情報 詳細情報について
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- CRID
- 1390001204903879424
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- NII論文ID
- 130004115167
- 10004923548
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- NII書誌ID
- AN00166576
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- ISSN
- 1881588X
- 0021437X
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可