混合性結合組織病（ＭＣＴＤ）のステロイド治療中に発症した真性皮膚結核の１例

DOI PubMed 被引用文献2件 参考文献19件

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  • A Case of Cutaneous Tuberculosis Associated with Steroid Therapy for Mixed Connective Tissue Disease.

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Patients receiving immunosuppressive therapy, such as adrenocorticosteroids, are high risk groups of tuberculosis. We report a case of cutaneous tuberculosis associated with steroid therapy for mixed connective tissue disease. A 63-year-old female was hospitalized after 6 months' treatment with prednisolone for connective tissue disease and bilat -eral abnormal shadows were revealed on her chest X-ray films. As her sputum smear was positive for acid-fast bacilli, the patient was transferred to our hospital for isolation and treatment. After three months' treatment with INH, RFP and EB, she complained the swelling of her left palm, left arm, and right leg, and skin puncture was performed. As smears of fluid aspirated from the swelling showed acid-fast bacilli, and fluid PCR tests showed positive for M. tuberculosis, she was diagnosed as cutaneous tuberculosis (scrofuloderma). In spite of administration of antituberculous agents, the swellingshowed little improvement.<BR>Therefore, the dose of prednisolone was reduced and cutaneous lesions were resected by surgery. High risk of tuberculosis should be considered when a patient administered immunosuppressive drugs, such as adrenocorticosteroids.

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  • 結核

    結核 73 (9), 557-562, 1998

    一般社団法人 日本結核病学会

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