Rapid Determination of Benzene Metabolites Phenol and p-Cresol in the Urine of Petrol Station Workers by Gas Chromatography

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抄録

The determination of phenol and p-cresol in urine has been suggested as a suitable biomarker for the monitoring of benzene exposure of pump workers employed in petrol stations. A method for efficiently extracting a wide variety of drugs from urine for toxicological analysis by gas chromatography is presented. The sensitivity of the method is sufficient to monitor normal levels of phenol and p-cresol after exposure to benzene vapors. The detection limit of the method is low enough to measure urinary phenol and p-cresol at a concentration of 0.1 mg/l. The overall recoveries of urinary phenol and p-cresol relative to the internal standard, DPA, ranged between 95 and 96.5%. Our gas chromatographic method is a rapid, precise and economical one suitable to measure the metabolite benzene also in routine monitoring of phenol and p-cresol.

収録刊行物

  • Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 16(6), 589-591, 2000-06-10

    社団法人 日本分析化学会

参考文献:  16件中 1-16件 を表示

  • <no title>

    YARDLEY-JONES A.

    Br.J.Ind.Med. 48, 437, 1991

    被引用文献2件

  • <no title>

    BARTAK P.

    J.Chromatogr. 867, 281, 2000

    被引用文献1件

  • <no title>

    BURES J.

    Gas-Lek-Cesk 129, 123, 1990

    被引用文献1件

  • <no title>

    ZULOAGA O.

    J Chromatogr. 849, 225, 1999

    被引用文献1件

  • <no title>

    STERNITZKE A.

    Food-Chem.-Toxicol. 30, 771, 1992

    被引用文献1件

  • <no title>

    ONG C. N.

    J.Chromatogr.B 660, 1, 1994

    被引用文献2件

  • <no title>

    ASTIER A.

    J.Chromatogr. 573, 318, 1992

    被引用文献2件

  • <no title>

    SABOURIN P. J.

    Anal.Biochem. 170, 316, 1988

    被引用文献2件

  • <no title>

    VENINGEROVA M.

    J.Chromatogr. 657, 103, 1994

    被引用文献2件

  • <no title>

    DASGUPTA A.

    J.Chromatogr.B 689, 415, 1997

    被引用文献1件

  • <no title>

    WANG Y. H.

    Xhung-Hua-Yu-Fang-I-Hsueh-Tsa-Chih. 25, 265, 1991

    被引用文献1件

  • <no title>

    KALF G. A. F.

    Ann.Rev.Pharmacol. 37, 399, 1987

    DOI 被引用文献1件

  • <no title>

    MALTONI C.

    Environ.Health Perspect 82, 109, 1989

    DOI 被引用文献1件

  • <no title>

    MURRAY K. E.

    J. Chromatogr. 431, 143, 1988

    DOI 被引用文献2件

  • <no title>

    DIRMIKIS S. M.

    J.Chromatogr. 94, 169, 1974

    DOI 被引用文献1件

  • <no title>

    EADSFORTH C. V.

    Analyst 109, 159, 1984

    DOI 被引用文献1件

各種コード

  • NII論文ID(NAID)
    10004955025
  • NII書誌ID(NCID)
    AA10500785
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    09106340
  • NDL 記事登録ID
    5380251
  • NDL 雑誌分類
    ZP4(科学技術--化学・化学工業--分析化学)
  • NDL 請求記号
    Z54-F482
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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