オキセサゼイン軟膏によるこう門手術後とう痛の管理

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  • Oxethazaine Ointment. A Useful Easy and Safe Alternative for Pain Control After Anal Surgery.

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Oxethazaine is the strongest and long acting local anesthetic and, is long applied as an analgesic for gastric pain. The ointment including 2.5% Oxethazaine powder was prepared, and its pain control after anal surgery was investigated. Patients and method ; A total of 136 patients underwent anal surgery at our outpatient clinic between Dec. 1998 and June 1999, and Oxethazaine ointment was used as necessary. All received the 35mg diclofenac sodium, the base analgesic, twice a day. The extent of the subjective pain (0 : slight, 1 : mild, 2 : tolerable, 3 : agonizing), side effect, times of the local application were studied. Results ; By application of the ointment, pain severity decreased from 1.9 to 0.6 on the day of operation and on the 7th postoperative day 1.1 to 0.4. All except 5 patients could control the pain by about 4 times a day application of Oxethazaine ointment with two tablets of 35mg diclofenac sodium. No side effect including headache and no systemic sign were noticed. Oxethazaine is not soluble in most fluids and only the solved part showed its effect, this peculiar character of Oxethazaine is why Oxethazaine ointment has long effectiveness and safety. From this study it was concluded that Oxethazaine ointment is a safe and easy way to control pain after anal surgery. With this method, day surgery for anal disease can be strongly promoted.

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