骨軟骨腫から悪性転化したと考えられた上顎前歯部に生じた骨肉腫の１例

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  • A case of osteosarcoma of the anterior region of the maxilla, apparently resulting from malignant transformation of osteochondroma.

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A case of osteosarcoma is reported. The tumor was localized in the anterior region of the maxilla, where osteosarcoma rarely originates, and was thought to result from malignant transformation of osteochondroma, which had recurred in the same region. The patient was a 45-year-old woman. She underwent tumor enucleation in the anterior region of the maxilla twice, 5 year 4 months and 2 years 10 months previously, to treat exostosis and osteochondroma, respectively. As she noticed a tumor in the same region, she consulted our department again on October 30, 1991. A painless, relatively well-demarcated, bone-like hard tumor measuring 26×20×15mm was detected in the alveolar bone of 3+3. Radiography disclosed a radiopaque area partly exhibiting a sun-ray-like appearance. The pathological diagnosis based on examination of a biopsy specimen was osteochondroma. However, malignancy was suspected because of recurrence and the distinctive radiographic characteristics of the lesion. Thus, partial resection of the maxilla was performed, and a diagnosis of osteosarcoma was finally made. There has been no recurrence or metastasis as of 7 years after operation and the patient remains healthy.

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